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Index > Protein center > AVPR1A(Gene name) > Human
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  • AVPR1A (Gene name),
  • Vasopressin V1a receptor (Protein name ),  V1AR_HUMAN from NCBI database.
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  • General Annotation
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  • Gene name:
    AVPR1A(AVPR1);
    Protein name:
    Vasopressin V1a receptor(V1aR);
    Alternative:
    Antidiuretic hormone receptor 1a;AVPR V1a;Vascular/hepatic-type arginine vasopressin receptor;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system. Has been involved in social behaviors, including affiliation and attachment.
    Subcellular Location:
    Cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    418
    Sequence:
    50:
    MRLSAGPDAG | PSGNSSPWWP | LATGAGNTSR | EAEALGEGNG | PPRDVRNEEL | 
    100:
    AKLEIAVLAV | TFAVAVLGNS | SVLLALHRTP | RKTSRMHLFI | RHLSLADLAV | 
    150:
    AFFQVLPQMC | WDITYRFRGP | DWLCRVVKHL | QVFGMFASAY | MLVVMTADRY | 
    200:
    IAVCHPLKTL | QQPARRSRLM | IAAAWVLSFV | LSTPQYFVFS | MIEVNNVTKA | 
    250:
    RDCWATFIQP | WGSRAYVTWM | TGGIFVAPVV | ILGTCYGFIC | YNIWCNVRGK | 
    300:
    TASRQSKGAE | QAGVAFQKGF | LLAPCVSSVK | SISRAKIRTV | KMTFVIVTAY | 
    350:
    IVCWAPFFII | QMWSVWDPMS | VWTESENPTI | TITALLGSLN | SCCNPWIYMF | 
    400:
    FSGHLLQDCV | QSFPCCQNMK | EKFNKEDTDS | MSRRQTFYSN | NRSPTNSTGM | 
    418:
    WKDSPKSSKS | IKFIPVST
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    KEGG:
    MIM:
    SMR:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human V1aR
    Cat.:
    E9136r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human V1aR
    Cat.:
    E9136h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human V1aR
    Cat.:
    E9136m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human V1aR
    Cat.:
    U9136h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human V1aR
    Cat.:
    U9136r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human V1aR
    Cat.:
    U9136m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human V1aR
    Cat.:
    P9136Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human V1aR
    Polyclonal Antibody for Human V1aR
    Cat.:
    P9136Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human V1aR
    Monoclonal Antibody for Human V1aR
    Monoclonal Antibody for Human V1aR
    Protein for Human V1aR
    Protein for Human V1aR
    Protein for Human V1aR

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    Precision
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    Linearity
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    References
    1. 1.
      "Molecular cloning, sequencing, and functional expression of a cDNA encoding the human V1a vasopressin receptor."
      Thibonnier M. , Auzan C. , Madhun Z. , Wilkins P. , Berti-Mattera L. , Clauser E.
      J. Biol. Chem.269:3304-3310(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Liver.
    2. 2.
      "Cloning, functional expression and tissue distribution of human cDNA for the vascular-type vasopressin receptor."
      Hirasawa A. , Shibata K. , Kotosai K. , Tsujimoto G.
      Biochem. Biophys. Res. Commun.203:72-79(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Liver.
    3. 3.
      "Functional vasopressin V1 type receptors are present in variant as well as classical forms of small-cell carcinoma."
      North W.G. , Fay M.J. , Longo K.A. , Du J.
      Peptides18:985-993(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Lung.
    4. 4.
      "Expression of all known vasopressin receptor subtypes by small cell tumors implies a multifaceted role for this neuropeptide."
      North W.G. , Fay M.J. , Longo K.A. , Du J.
      Cancer Res.58:1866-1871(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    5. 5.
      "cDNA clones of human proteins involved in signal transduction sequenced by the Guthrie cDNA resource center (www.cdna.org)."
      Kopatz S.A. , Aronstam R.S. , Sharma S.V.
      Submitted (2003-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Liver.
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Lung.
    7. 7.
      "Transmission disequilibrium testing of arginine vasopressin receptor 1A (AVPR1A) polymorphisms in autism."
      Kim S.J. , Young L.J. , Gonen D. , Veenstra-VanderWeele J. , Courchesne R. , Courchesne E. , Lord C. , Leventhal B.L. , Cook E.H. Jr. , Insel T.R.
      Mol. Psychiatry7:503-507(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ROLE IN SOCIAL BEHAVIOR
    8. 8.
      "A C-terminal segment of the V1R vasopressin receptor is unstructured in the crystal structure of its chimera with the maltose-binding protein."
      Adikesavan N.V. , Mahmood S.S. , Stanley N. , Xu Z. , Wu N. , Thibonnier M. , Shoham M.
      Acta Crystallogr. F61:341-345(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.8 ANGSTROMS) OF 362-418
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